Butler has a history of pulling off upsets in the NCAA Tournament, but the fourth-seeded Bulldogs face a tough matchup against No. 1 seed North Carolina in the South Region semifinals Friday in Memphis, Tenn. Butler is trying to knock off a No. 1 seed for the third time after doing so in 2010 and 2011 en route to back-to-back championship game appearances.

Seventh-seeded South Carolina takes part in the school's first Sweet 16 under the current NCAA Tournament format when it faces third-seeded Baylor on Friday night in the East Region at Madison Square Garden in New York. And Gamecocks coach Frank Martin, whose team advanced thanks to what some are calling the biggest win in school history -- an 88-81 upset of second-seeded Duke on Sunday night, wants to make sure his team isn't satisfied just to be there.

UCLA knows what it takes to defeat Kentucky, and the third-seeded Bruins try to take down the No. 2 seed Wildcats for the second time this season when they meet in the NCAA Tournament Sweet 16 on Friday at the FedEx Forum in Memphis, Tenn. UCLA defeated Kentucky on Dec. 3 in 2015 and again in 2016, each time when the Wildcats were ranked No. 1 in the coaches' poll.

Florida and Wisconsin are two of the most impressive teams in the NCAA Tournament, and one is about to move a step closer to another Final Four trip. The fourth-seeded Gators and eighth-seeded Badgers square off Friday in New York City in an intriguing Sweet 16 matchup in the East Region.