Chi. White Sox 9, Minnesota 0
Martin Perez threw six no-hit innings and Andrew Vaughn, Andrew Benintendi and Michael A. Taylor each homered to lead the Chicago White Sox to a 9-0 victory over the visiting Minnesota Twins in the opener of their three-game series on Monday afternoon.
Kansas City 11, Milwaukee 1
Kris Bubic tossed six innings of three-hit ball in his first start in almost two years as the Kansas City Royals spoiled Milwaukee's home opener 11-1 on Monday, keeping the Brewers winless in four games.
Baltimore 8, Boston 5
Cedric Mullins smashed a two-run double during Baltimore's four-run first inning and drove in two more runs later in the game as the Orioles won their home opener by defeating the Boston Red Sox 8-5 on Monday afternoon.
Philadelphia 6, Colorado 1
Edmundo Sosa hit a go-ahead, two-run double with two outs in the seventh inning and Kyle Schwarber followed with a two-run homer as the Philadelphia Phillies celebrated their home opener with a 6-1 win over the Colorado Rockies on Monday.
Cincinnati 14, Texas 3
Elly De La Cruz hit two tape-measure home runs, doubled, singled and drove in a career-high seven runs to lead the Cincinnati Reds to a 14-3 rout of the visiting Texas Rangers Monday night.
NY Mets 10, Miami 4
Pete Alonso hit a grand slam to power a seven-run fifth inning Monday night for the New York Mets, who rolled to a 10-4 win over the host Miami Marlins in the opener of a three-game series.
Tampa Bay 6, Pittsburgh 1
Jake Mangum went 4-for-4 with a double, two RBIs and two stolen bases in his second big-league game, propelling the host Tampa Bay Rays past the Pittsburgh Pirates 6-1 on Monday.
Toronto 5, Washington 2
Bowden Francis did not allow a hit until the sixth inning, Andres Gimenez homered and the Toronto Blue Jays defeated the visiting Washington Nationals 5-2 on Monday night.
LA Angels 5, St. Louis 4
Mike Trout hit two sacrifice flies as the visiting Los Angeles Angels rallied past the St. Louis Cardinals 5-4 in 10 innings on Monday.
San Francisco 7, Houston 2
Jordan Hicks twirled six shutout innings, Wilmer Flores socked his third home run and the visiting San Francisco Giants defeated the Houston Astros 7-2 on Monday in the opener of a three-game interleague series.
San Diego 7, Cleveland 2
Gavin Sheets drove in four runs Monday night and Kyle Hart earned his first major league win as the San Diego Padres opened the season 5-0 for the first time in franchise history with a 7-2 victory over the visiting Cleveland Guardians.
Detroit 9, Seattle 6
Riley Greene homered in a six-run first inning as the Detroit Tigers defeated the host Seattle Mariners 9-6 on Monday night for their first victory of the season.
Chi. Cubs 18, Athletics 3
Michael Busch christened Sutter Health Park as a major league stadium with a first-inning home run, Carson Kelly hit for the cycle, and the Chicago Cubs spoiled the Athletics' debut at their new home in West Sacramento, Calif., with an 18-3 shellacking on Monday.
LA Dodgers 6, Atlanta 1
Teoscar Hernandez hit a two-run home run in the first inning, Tyler Glasnow went five scoreless and the Los Angeles Dodgers remained perfect on the season with a 6-1 home victory over the sluggish Atlanta Braves on Monday.