Two of the more frustrated teams in the majors begin a four-game series in Toronto on Monday as the Los Angeles Angels visit the Blue Jays, who sit five games under .500 following five straight losses. The Angels have won five of their last six but show no signs of ending their season-long offensive woes.

After falling short in their attempt to complete a sweep in St. Louis, the Detroit Tigers return to Comerica Park to begin a seven-game homestand that starts Monday with the opener of a three-game set against the Milwaukee Brewers. Detroit followed a 13-1 triumph over Minnesota with another double-digit output in its series-opening victory at St. Louis and edged the Cardinals in the middle contest before having the tables turned Sunday, when it dropped a 2-1 decision.

The struggling Miami Marlins will have a new manager when they try to snap a three-game skid Monday in the opener of a four-game series with visiting Arizona. The Marlins reportedly will announce Jeff Conine, who played for the team for eight seasons beginning with the inaugural 1993 campaign, as the successor to Mike Redmond, who was fired Sunday. 

The St. Louis Cardinals look to put an end to their offensive struggles when they visit the New York Mets on Monday for the opener of the four-game series between the division leaders. St. Louis, which sits atop the National League Central, avoided a three-game home sweep at the hands of Detroit by posting a 2-1 triumph on Sunday.

Corey Kluber is coming off an epic performance as he takes the mound for the Cleveland Indians on Monday to face the host Chicago White Sox. Kluber, who struck out a career-best 18 and allowed one hit without a walk over eight innings in a 2-0 victory over St. Louis on Wednesday, now takes aim at stopping Chicago’s five-game winning streak.

Highly touted prospect Lance McCullers makes his major-league debut on Monday, when he starts for the Houston Astros against the visiting Oakland Athletics in the opener of their three-game series. The 21-year-old McCullers was a first-round pick in 2012 and dominated at Double-A Corpus Christi this season before being promoted to Triple-A Fresno on Thursday.

After years of despair, there is a glimmer of hope surrounding the Philadelphia Phillies, who bring a five-game winning streak into Monday’s series opener against the host Colorado Rockies. The Phillies are an even 8-8 in May while Colorado has lost 19 of their past 25 games following a 7-2 start.