Red Sox 5, Reds 4: Anthony Ranaudo picked up his second major-league win in as many chances and Mike Napoli homered as visiting Boston completed a two-game sweep of Cincinnati.

Brock Holt scored twice and Daniel Nava and Yoenis Cespedes each drove in a run for the Red Sox, who finished up the eight-game road trip 5-3 - their first winning trip of longer than three contests in 2014. Ranaudo (2-0) was reached for four runs and eight hits in six innings, and Edward Mujica worked around back-to-back singles leading off the ninth for his third save.

Mike Leake (9-11) hit a solo homer but was knocked around for five runs on eight hits in five innings. Skip Schumaker added a solo blast among two hits and Kris Negron scored twice for the Reds, who dropped 3 1/2 games behind the St. Louis Cardinals in the race for the second National League wild-card spot.

Boston got to Leake for a pair of runs in the first inning on an RBI single from Nava and Napoli’s run-scoring fielder’s choice, but Cincinnati got on the board with a sacrifice fly in the third before grabbing the lead in the fourth. Schumaker’s lined shot to right tied it up before Leake gave himself a lead with his second homer of the season to left one batter later.

Leake did not waste much time surrendering that advantage as Holt doubled and scored on Cespedes’ two-out single in the fifth before Napoli went the opposite way with a two-run shot to right-center. Negron tripled and scored on Todd Frazier’s sacrifice fly in the bottom of the inning, but Ranaudo got through the sixth unscathed and Burke Badenhop and Junichi Tazawa each posted a perfect inning before handing it off to Mujica.

GAME NOTEBOOK: Cespedes was lifted in the seventh inning for a pinch hitter due to a right hand contusion. … Red Sox CF Jackie Bradley Jr. snapped an 0-for-35 drought with a single in the second inning. … Cincinnati, which has dropped four of five, kicks off a seven-game road trip at Colorado on Thursday before heading to St. Louis for a showdown with the Cardinals.